Metabolism after 40: What really changes?

Many people notice that after the age of 40, body weight seems to increase more easily, while losing weight becomes more difficult than before. Although metabolism is often blamed, experts point out that the changes taking place in the body have multiple causes. As we age, hormonal balance, body composition, physical activity levels, and lifestyle habits all change. This is why modern obesity management relies on an individualized, long-term approach. In line with this approach, Galenika introduced Olire®, a GLP-1 therapy indicated for the treatment of obesity and excess body weight, to the Serbian market. As part of a comprehensive approach, the company has also developed the Oli-support line of food supplements, designed to provide nutritional support for people working toward weight loss.
Metabolism changes—but it’s not the only reason
After the age of 40, muscle mass naturally begins to decline, while the body’s nutritional and energy needs also change. If physical activity decreases at the same time, the body burns less energy than it did before, making weight management more challenging. However, experts emphasize that a slower metabolism is not the only reason for weight gain. Sleep quality, stress levels, eating habits, and everyday lifestyle choices can be just as important.
Why is preserving muscle mass important?
During the process of losing excess body weight, the goal is not simply to lose kilograms, but also to preserve normal muscle mass. Based on this understanding, Galenika developed the Oli-support line of food supplements, designed to provide nutritional support for people working toward weight loss.
One of the products in this line is Oli-Muscle, a food supplement containing essential amino acids that help maintain normal muscle mass and support an increase in muscle mass.
Oli-support products may be used alongside Olire® or other GLP-1 therapies as part of a comprehensive approach, in accordance with the advice of a healthcare professional.
Fiber becomes even more important
As lifestyle habits and dietary patterns change, digestive function often changes as well. Adequate dietary fiber intake is important for maintaining normal bowel function and supporting everyday digestive comfort.
As part of the Oli-support line, Oli-Lax provides an additional source of psyllium, galactooligosaccharides, and the bacterial strain Akkermansia muciniphila, supporting intestinal health and digestion as part of a balanced approach to weight loss.
Age is not a barrier to change
Modern medicine recognizes obesity as a complex metabolic disease rather than simply the result of unhealthy lifestyle habits. Sustainable weight loss rarely depends on willpower and discipline alone—it requires a multidisciplinary approach.
Rather than seeing age as an obstacle, it should be viewed as another reason to take a planned, long-term approach to health. Guided by this understanding of modern obesity management, Galenika introduced Olire®, a GLP-1 therapy indicated for the treatment of obesity and excess body weight, and developed the Oli-support line of food supplements to provide nutritional support for people working toward weight loss.
The combination of medical therapy when indicated, healthy nutrition, regular physical activity, and appropriate nutritional support is part of a comprehensive approach aimed at achieving sustainable results and improving quality of life.
This article was originally published on UNA: https://una.rs/zivot/zdravlje/metabolizam-posle-40-sta-se-zaista-menja